RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-125b-1
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR etc.
Target
SFRP5
Pathway
NA
PubMed ID
Title
MiR-125b Regulates SFRP5 Expression to Promote Growth and Activation of Cardiac Fibroblasts
Year
2016
Function
"miR-125b promotes the proliferation and migration of cardiac fibroblasts (CFs) and inhibits their apoptosis, while SFRP5 exhibits the opposite effects.These results indicate that miR-125b can regulate SFRP5 expression and thus influence the growth and activation of CFs."